See also our related blog for the Pediatric Preclinical Testing Initiative.

Sunday, January 29, 2012

Our thanks to the Ethan Jostad Foundation

We are grateful to partner with the Ethan Jostad Foundation for Childhood Cancer in the search for treatments of alveolar rhabdomyosarcoma.  This foundation has both patient/family assistance and research as the center of their mission.  We are thankful for the gift of $11,400 that supports the preclinical studies of a specific new agent potentially capable of stopping tumor cell spreading (metastasis).  These studies will specifically employ our genetically-engineered mouse model of alveolar rhabdomyosarcoma.  We are honored to be part of Ethan's rememberance.     
[ pictured:  Guangheng Li and Charles Keller (left) with Chris and Kim Jostad (right) ]  

Tuesday, January 24, 2012

Graphics Volunteer Needed

We are hoping to work with a volunteer in the community with graphic arts/communication experience.  The project is about 6 weeks long and may take 8-12 hours a week.  If you have time and interest, please contact Charles at keller (at)   with thanks, the Keller Lab team

Tuesday, January 17, 2012

Congratulations, Ken and Anu!

Congratulations to authors Ken and Anu whose manuscript describing the role of Protein Kinase C iota in rhabdomyosarcoma was accepted today to the journal, Oncogene.  Co-authors include lab alumni Laura and Sheila, UTHSCSA biostatistics collaborators Joel Michalek and Lee Ann Zarzabal, Mayo PKC biology collaborators Capella Weems and Alan Fields, and long-time sarcoma pathologist collaborator Brian Rubin at Cleveland Clinic.  This work was supported by by NIH/NCI grant 1R01CA133229-04 and -05 awarded to the Keller lab and NIH/NCI grant 4R01CA081436-13 and the V Foundation for Cancer Research awarded to Dr. Fields.  
For a full list of KellerLab & collaborator publications in the last year and beyond, see .
[ 2/22/2012:  Ken's article, Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma, is now online here.

Friday, January 13, 2012

Congratulations, Anu!

(01/13/12):  Article entitled, "(18) F-FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models" is now online here as PMID 22238194.  

(12/17/11)  Many congratulations to lab alumni, Anu, on her study from our lab of PET scan monitoring of targeted therapy responses in alveolar & embryonal rhabdomyosarcoma, which has been accepted for publication in Pediatric Blood & Cancer.  Co-authors include current lab member Jinu, lab alumni Laura & Suresh, and collaborators Lee Ann Zarzabel & Joel Michalek (UTHSCSA), Stan McHardy (SWRI), Doug Hawkins (Seattle Children's Hospital) and Suman Malempati (OHSU Doernbecher Children's Hospital).