Tuesday, August 12, 2014

Muscle Differentiation as Rhabdomyosarcoma Therapy

Matthew from our lab wrote this commentary in Cancer Cell, which frames the question of how soon myo-differentiation therapy will be feasible for childhood muscle cancer.  The commentary discusses the article here.  Graphic illustration by Nick Escobar. 

Wednesday, July 23, 2014

a tool for innovation

We are grateful to the Alex' Lemonade Stand Foundation for our new instrument, a Form1 3D printer. With this device we can generate custom tissue culture incubation chambers. This project is pioneered by Kirsten and Richard this Summer.  stay tuned!

Wednesday, July 16, 2014

congratulations, Jinu!

[07/14/14]  The article, Lineage of origin in rhabdomyosarcoma informs pharmacological response, is now available here.  
[06/03/14]  Congratulations to Jinu whose paper was recently accepted for publication to Genes & Development.  This work was funded in part by NIH as well as the Scott Carter Foundation.  Clinical translation is hopefully possible, and thus additional preclinical studies with cooperative group and pharmaceutical partners are in discussion.  We are grateful to all our collaborators, especially Atiya Mansoor (OHSU), Joel Michalek and Ben Ehler and Monica Suelves (IMPPC).  

Wednesday, July 9, 2014

Welcoming Kirsten

We are excited to have Kirsten on our team this Summer.  Kirsten is an orthopedic surgery resident with a keen interest in tissue engineering.  

" I graduated from the University of Missouri–Kansas City School of Medicine in 2011 with my MD and BA in Biology through the combined MD/BA program.  Shortly, thereafter I moved to Portland to start my 5 years of residency training in Orthopaedic Surgery at OHSU.  My interests in the field include joint reconstruction and orthopaedic oncology.   I hope to bring the unique perspective of a surgeon scientist to Dr. Keller's lab as we work to develop a 3D in vitro sarcoma model system.  In my free time I enjoy playing disc golf and spoiling my cats.  Kirsten "

Sunday, July 6, 2014

Welcoming Richard

We are privileged to have engineering undergraduate student, Richard, join our team as a Summer intern.  

"I am a sophomore at The University of Notre Dame. This opportunity at the Keller Laboratory excites me because it gives me a chance to challenge myself and develop a deeper understanding of how research is conducted. As an individual who has been affected by the loss of loved ones to various forms of cancer, the implications of the research at The Keller Laboratory are especially important to me as well as thousands of others who are personally affected by cancer."

Monday, June 9, 2014

Welcoming Renae!

We are excited to have on our team Renae, a Summer student investigating EphB4 and EphrinB2 in childhood cancers.  
"I will be starting my second year at Pacific University in the Fall where I am studying biology and will graduate in 2016. After graduating I hope to enroll in a MD/MS program in the hope that it will allow me to build a future career working both in the lab and with patients. I became interested in pediatric oncology in high school and am grateful to now have the opportunity to be working in a lab that is so focused on discovering new and better treatments and hope to do the same in the future."