Monday, April 14, 2014

Imran's paper published in PNAS

Many congratulations to Imran for his publication, PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma, today in the Proceedings of the National Academy of Sciences of the USA.  This study was a collaboration of the Tyner, Druker and Keller laboratories - highlighting some key growth factor receptor targets in this disease.  This study was funded in part by the Howard Hughes Medical Institute, the National Cancer Institute, and the Joanna McAfee Childhood Cancer Foundation.       

Friday, April 4, 2014

COG Spring meeting

The Fall COG meeting was held in St Louis this past week.  The soft tissue sarcoma session, and corresponding Ewing's-Rhabdomyosarcoma Biology session, were very productive.  

Saturday, March 29, 2014

Northwest Sarcoma Foundation initiative

We are grateful for the $25,000 directed gift from the Northwest Sarcoma Foundation that facilitates Seattle-Portland collaboration in the genetic and functional characterization of adult bone and soft tissue sarcomas.  This is the second year of this program, which supports collaboration between our laboratory and Dr. Robin Jones at the Seattle Cancer Care Alliance.  

Thursday, March 27, 2014

SARC Sarcoma Developmental Research Program

We are grateful to the SARC SPORE pilot grants program which has awarded a 2nd year of funding to our collaboration with Dave Langenau's lab at MGH evaluating myodifferentiation therapies for rhabdomyosarcoma.   

Tuesday, March 25, 2014

Congratulations, Jinu!

Many congratulations to Jinu, whose grant application entitled, "Molecular Reversal of Relapse in Childhood Muscle Cancer" was chosen for funding by the Friends of Doernbecher Foundation!

"Derivation of Myogenic Progenitors Directly From Human Pluripotent Stem Cells"

Lab alumnist Tohru Hosoyama has recently published a very nice study entitled, "Derivation of Myogenic Progenitors Directly From Human Pluripotent Stem Cells Using a Sphere-Based Culture" in the journal, Stem Cells Translational Medicine.  This is work from Tohru's second postdoctoral fellowship with mentor Dr. Masatoshi Suzuki.  Tohru is now an Assistant Professor in the Dept. of Surgery and Clinical Sciences, Yamaguchi University, Japan.  It has always been a pleasure to follow Tohru's work, which is both innovative and impactful.     

Wednesday, March 19, 2014

let's help Lara...

... shave her head, for adolescent and young adult cancer research?  Click here to learn more, see Lara's video and contribute to this bold effort!   The shaving event happens May 31!