See also our related blog for the Pediatric Preclinical Testing Initiative.

Tuesday, November 16, 2004

Alveolar Rhabdomyosarcoma mouse model revealed

Charles Keller, Ben Arenkiel, Nabeel El-Bardeesy, Cheryl Coffin, Ronald DePinho, Mario Capecchi.  “Alveolar Rhabdomyosarcomas in Conditional Pax3:Fkhr Mice: Cooperativity of Ink4a/ARF and Trp53 Loss of Function,” Genes & Development, 18(21) 2614-26, November 2004 [PubMed UID 15489287]

Monday, November 15, 2004

Pax3:Fkhr biology in Embryogenesis

Charles Keller, Mark S. Hansen, Cheryl Coffin, Mario Capecchi.  “Pax3:Fkhr interferes with Embryonic Pax3 and Pax7 Function: Implications for Alveolar Rhabdomyosarcoma Cell of Origin,” Genes & Development, 18(21) 2608-13, November 2004 [PubMed UID 15520281]

  Comment in: Nicola McCarthy. Divining forks for developing tumours.  Nature Reviews | Cancer.  2004; Volume 4:835