See also our related blog for the Pediatric Preclinical Testing Initiative.

Monday, August 4, 2008

Rhabdomyosarcoma Therapeutics Study published today in Oncogene

Congratulations to Eri and her co-authors Koichi and Mandy on the publication today of their study, "PDGFR-A is a Therapeutic Target in Alveolar Rhabdomyosarcoma". Our paper was published in the advanced online edition of the journal Oncogene. This study reveals a very promising new category of non-chemotherapy drugs to try in this disease, as we have done in our mouse model. Moving our results to the clinic will require close attention and some further study of how tumors become resistant to this drug class in about 1/3 of cases. These follow-up studies are currently being undertaken by Corrine and Eri. Further description of our study is given on Newswise.

[ UPDATE (Nov 2008) The formal version of Eri's article is now available. ]