Mice, Cat scans aid child cancer research

This was an article featured in The San Antonio Express News, describing how with micro CT scans scientists can create a large, three-dimensional computer image of embryos to study. ..."We take an embryo that is intact but we can use the computer to do a cutaway to view to the interior structures," said Keller, a pediatric oncologist at the Children's Cancer Research Institute who is studying brain and muscle tumors. Click here to read more.

Cindy Tumiel. "Mice CAT scans aid child cancer research." San Antonio Express News, Metro Section, first page. [interview, figure]

microCT-based Virtual Histology

John T. Johnson, Mark S. Hansen, Isabel Wu, Lindsey J. Healy, Christopher R. Johnson, Greg M. Jones, Mario R. Capecchi, Charles Keller.  “Virtual Histology of Transgenic Mouse Embryos for High-Throughput Phenotyping,” PLoS Genetics, 2006, 2(4)e61 [COVER ARTICLE] [PubMed UID 16683035]

• Comment in: Magdalena Skipper. No Mickey-Mouse phenomics.  Nature Reviews | Genetics.  2006; Volume 7:409
• Comment in: Research Highlights.  Nature Methods, July 2006; Volume 3 Number 7 Page 497
• Comment in: Susannah Veith. “New ‘virtual’ histology method bolsters visualization of mouse embryos.”  Biophotonics International, July 2006, pp. 24-25
• Comment in: staff writer. Virtual slicing gives faster testing.  New Scientist (Special Reports; Tech), 9 May 2006, Issue 2550, Page 21
• Comment in: Julian Josephson. Mouse Embryos in 3-D.  Environmental Health Perspectives (EHP) – a journal of the NIEHS, October 2006; Volume 114 Number 10 Pages A596-A599
• Comment in: Dennis Meredith. Better than Slice-and-Dice. HHMI Bulletin, February 2007; Volume 20(1)

Koichi Nishijo (Postdoctoral Fellow, starts 04/01/2006)

Koichi recieved Alex's Lemonade Stand Young Investigator Award for his Application: Mediators of Metastasis in Alveolar Rhabdomyosarcoma ($60,000 awarded over 2 years, 7/01/06 - 06/30/06).

He also won a poster prize ($500), Genomic Integrity and Tumor Development Program Retreat.

He also is an Invitee-Attendee to the 2006 AACR "Molecular Biology in Clinical Oncology" Workshop.