NCI Rare Cancer Workshop

Pediatric sarcoma research had good representation at the NCI Rare Cancers with High Mortality: Challenges for Cancer Prevention and Treatment workshop in Bethesda yesterday and today. This workshop of more than 200 investigators, consumer advocates, patient advocates and policy makers examined approaches that might be taken to promote the development of resources and infrastructure necessary for new therapy development (ie, biorepositories, cancer genome and epi-genome studies, mouse models, clinical trials infrastructure and patient advocacy networks. At the workshop, Charles presented a main session talk on Mouse Models, and colleagues Drs. Frederic Barr (rhabdomyosarcoma, U Penn) and Jeff Toretsky (Ewing's sarcoma, Georgetown University) were moderators for a breakout session.

[above right: Jeff, Charles and Fred]

Steve Lessnick visits GCCRI

We are grateful to our colleagues, Dr. Stephen Lessnick from the Huntsman Cancer Institute, to have given a seminar on Ewing's Sarcoma at GCCRI. Steve is a fellow pediatric hematologist-oncologist and physician-scientist who studies the genetics and biochemistry of the Ews:Fli translocation product in Ewing's Sarcoma. Steve also plays an important role in the Children's Oncology Group, demonstrating his commitment to move new findings from the bench to the bedside.

[above right: Steve and Charles at Mi Tierra, a favorite San Antonio breakfast spot.]

Dr. Catchpoole visits from Australia

It was an absolute pleasure to have had Dr. Daniel Catchpoole visit GCCRI from the Childhood Cancer Research Unit at the Children's Hospital at Westmead, Sydney, Australia. Dan presented results of his studies of novel topoisomerase inhibitors that have specific efficacy in rhabdomyosarcoma. Part of this work was done in collaboration with our laboratory as well, with more studies together to come. If you have time, please visit Dan's childhood cancer tumor bank website. Dan is one of the key people across the world working to increase the access that researchers have to tumor material -- so that scientific discovery and better treatments are found more quickly.

[ above right, top:  Dan is a cave guide.  Here he is braving a very narrow passage at Jenolan Cave, Australia ]

[above right, bottom:  Dan at the Far Country Cave, Australia ]

Welcoming Dustin !

We are happy to welcome graduate student Dustin Green for a rotation in our laboratory. Dustin graduated with a MS in Biology from Louisiana Tech University where his research in the lab of Dr. Mark DeCoster utilized a novel molecular printer to spatially control glial cell line growth. Dustin’s career goal is to perform research at the forefront of translational, bench-to-bedside approaches.

Holiday Fun

It's hard to say how exactly this Halloween-related movie got composited, but it represents our lab's complete postdoctoral team. and yes, that is actually Koichi's real hair.

Hunter (lab alumnist) travels to Copenhagen

As a workstudy student, Hunter was a valuable member of our laboratory this past year, especially where we were interfacing biology, engineering and bioinformatics. Having recently graduated from UTSA, he naturally headed oversees to get a broader world view. Of course, we're sure his next step should be graduate school - although that would be a loss to the music field, Hunter's other passion.

Scientific Exchange with Mayo Clinic Jacksonville

We are grateful to Dr. Al Copland and colleagues for the opportunity to share our work on Overcoming Resistance to RTK Inhibitors in Rhabdomyosarcoma with the outstanding group of 8 faculty in the Cancer Basic Science Research program at Mayo Clinic - Jacksonville. This group of highly accomplished scientists has, in a short number of years, created a highly synergistic and productive research unit with some of the most interesting work in cell & molecular signaling and tumor microenvironment work in cancer research. Charles is especially appreciative of his colleague, Al, for this invitation to present our work and share ideas on addressing key issues in rare (and sometimes not so rare) cancers.

[ above right: Charles & Al ]